Jardiance is a daily oral medication that is utilized to regulate blood sugar levels in those who suffer from type 2 diabetes.
This is accomplished by aiding the kidneys in removing glucose from the bloodstream via the urine.
Jardiance does not aid in weight reduction or blood pressure management However, it can assist in both. It can be used as part of a treatment program which may include exercise, diet, and medical treatment.
This drug received approval from the European Commission in May 2014. Since it is a relatively new medication that is still in its initial stages, the long-term effects of several years are not well-known.
Name of the trade: Jardiance
Name of the Generic: Empagliflozin
The class of drugs: SGLT2 inhibitors
Manufacturer Boehringer Ingelheim and Lilly Diabetes
What does Jardiance aid in the treatment of type 2 diabetes?
In removing excess levels of glucose in the body via the urine, Jardiance assists in enhance glycemic control for people suffering from Type 2 Diabetes. This may result in better HbA1c values, and may lower the risk of developing complications associated with diabetes.
Because glucose’s calories are eliminated out of the body. Weight loss could be a result of Jardiance. Since type 2 diabetes is highly related to weight – approximately 90% of people who are newly diagnosed with type 2 diabetes have a weight that is above the ideal which is beneficial to keeping an ideal weight.
Jardiance is used as a part of a treatment plan and it is crucial to keep other aspects in check including physical fitness in addition to Jardiance treatment.
Mechanism of action
Empagliflozin can be described as an SGLT2 inhibitor, a class of medications that assists in stopping sodium-glucose transport proteins that have been removed from kidneys’ bloodstream and reabsorbed into blood.
Empagliflozin permits a substantial volume of sugar eliminated by urine. It is believed that the SGLT2 protein is responsible for 90% percent of glucose returned to the blood.
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Who do you think Jardiance best suited to?
Jardiance is suggested from the National Institute of Clinical Excellence (NICE) as an option for treating type 2 diabetes in these conditions:
When exercise and diet don’t provide enough glucose-control
When metformin is not the right choice because of patient intolerance
Jardiance can also be used in conjunction with metformin when patients are at high danger of having hypoglycemia or is unable to use an Sulfonylurea. It is also possible to take alongside metformin or a the sulfonylurea.
Who should not be able to resist Jardiance?
It is not recommended to use Jardiance If you suffer from:
Type 1 diabetes
Severe kidney problems
Before you take Jardiance the first time, discuss with your doctor if:
Are you suffering from kidney problems?
Are you pregnant or plan to be expecting or planning to become
Are you breastfeeding or are you planning to breastfeed?
Are you suffering from liver issues?
Are you suffering from low blood pressure?
Get blood pressure medication
Are you suffering from high cholesterol levels?
Are you a victim for urinary tract infections
Are you 65 years old or more
Are you following a low-salt diet
What should Jardiance be handled?
Jardiance can be administered orally, and is generally taken every morning. It can be taken either with or without food.
The medication is initially prescribed as a 10mg dosage but the maximum dose is 25 mg. Your doctor can alter the dose of your medication to ensure you are getting the most benefit You should not use Jardiance in lower or higher doses than what is recommended.
If you are unable to take an dose, it is recommended to start taking it whenever you remember. But, do not take an additional dose to make up for the missed medication. Likewise, if it’s almost time to take your next dose, then you can avoid the missed dose.
Jardiance is best stored at room temperature away heat and moisture. It should be kept in the original container. It is essential to ensure that it’s out of sight and reach of children.
What are the possible side negative effects of Jardiance?
The negative side consequences of Jardiance are:
Urinary issues – such as frequent urges to urinate or a lack of being able to urinate.
The increased risk of urinary tract infections
The signs of a genital infection include itching, pain or the appearance of a skin rash
If taken in conjunction by a medication that lowers blood glucose levels
The increase in cholesterol
Feeling tired , light-headed or fatigued
Note that the above list isn’t complete. It is recommended to consult the leaflet for patients that comes with the medication to get a complete list of possible side negative effects.
What do you do if you are taking an excessive dose
If you are taking an excessive dose of Jardiance make contact with your health care provider immediately to seek advice.
There are concerns about whether SGLT2 inhibitors can have a negative long-term impact on the kidneys. Invokana is part of the same drug class as Jardiance is associated with a decline in eGFR which is a measure used to assess kidney function.
As per the European Medicines Agency, the most commonly reported adverse reaction from Jardiance was hypoglycemia. This resulted when the drug was combined in combination with insulin or sulphonylurea.